Sedat Motor, Mukadder Canan Keskin, Recep Dokuyucu
2.144 428


Obesite yağ dokusunun aşırı artışı olarak
tanımlanır. Son yıllarda yapılan çalışmalar,
beyaz yağ dokusunun, adipokinler olarak
tanımlanan bir grup biyoaktif polipeptidi
üretip-sekrete edebilen endokrin bir organ
olduğunu ortaya çıkarmıştır. Yapılan bu
çalışmalarda adipokinlerin insülin direnci,
enflamasyon, hipertansiyon, kardiyovasküler
ve metabolik bozukluklar gibi obesite ile
ilişkili bir grup hastalığın gelişiminde önemli
role sahip olduğu gösterilmiştir. Bu derlemede
obezite ile ilgili tanımlanmış adipokinler,
sitokinler ve onların fonksiyonları hakkındaki
bilgiler verilmiştir.
Anahtar Kelimeler: Yağ dokusu, Obezite,
Adipokinler, Sitokinler

Anahtar kelimeler

Yağ dokusu, Obezite, Adipokinler, Sitokinler

Tam metin:


DOI: http://dx.doi.org/10.17944/mkutfd.16142


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