Bariatrik Cerrahi ile Kilo Kaybının Kardiyak Fonksiyonlara Etkisinin Ekokardiyografi İle Değerlendirilmesi

AHMET AKÇAY, İmran Ceren, Gürkan Acar, Huseyin Nacar, Mehmet Çelebi, Kemal Göçer, İdris Ardıç, Abdullah Sökmen
1.123 287

Öz


Amaç: Bariatrik cerrahi tedavi hızlı bir şekilde kilo kaybında çok etkili olmaktadır. Bu çalışmamızda obezite cerrahisi öncesi ve sonrasında biyokimyasal ve ekokardiyografik olarak kardiyak fonksiyonları inceledik.

Gereç ve Yöntem: Çalışmamıza prospektif olarak Genel cerrahi polikliniğinde bariatrik cerrahiye (laparoskopik sleeve gastrektomi) uygun olarak değerlendirilen, 23-55 yaş arası, morbit obez ( VKİ 47.8 ± 7.3 kg/m2 ) olan 30 (22 kadın ve 8 erkek ) hasta alınmıştır. Hastaların fizik muayene ve biyokimyasal testleri yapıldı. Bariatrik cerrahi öncesi ve 6 ay sonrası konvensiyonal ve doku doppler ekokardiyografi parametreleri, sol ve sağ ventrikül fonksiyonları, miyokard performans indeksleri (MPI), sol ve sağ atriyal volüm endeksleri ölçüldü.

Bulgular: VKİ cerrahi öncesi 47.8 ±7.3 kg/m2 iken 6 ay sonunda 34.1±7.1 kg/m2 ölçüldü (p<0.001).  Kalp hızı (p= 0.020) ve sistolik (p = 0.003) ve diyastolik kan basıncı (p = 0.009) ve plasma açlık glukoz (p<0.001) değerleri iki grup arasında anlamlı düşük bulundu. Sol ventrikül diyastol sonu çapı, sol ventrikül kitlesi, Triküspit E/A oranı ve sol atrium volüm indeksi anlamlı olarak farklı idi (sırasıyla p= 0.026, p= 0.010, p<0.001, p= 0.006 ). Sol ventrikül septal MPI (0.44±0.06 ;    0.40±0.06, p=0.05) ve sağ ventrikül MPI anlamlı şekilde düştüğü gözlendi (0.43±0.08       ; 0.35±0.05, p<0.001).

 

Sonuç: Kilo kaybının morbid obez hastalarda kardiyak fonksiyonları iyileştirdiğini düşündürmektedir. Bulgularımız hastaların sistolik ve diyastolik fonsiyonlarında olumsuz değişme olmadığını, ayrıca  myokard performans indeksinin iyileştiği sonucunu ortaya koymuştur.

 


Tam metin:

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DOI: http://dx.doi.org/10.17944/mkutfd.66764

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